Four astronauts have to stay 1000 days in a space station around Earth in order to prove that a trip to Europa, one of Jupiter's moon, is possible. The experience goes well until something happens on earth.
Dave 失戀喪志，終日躲在姐姐家中避世，湊外甥以療情傷。一天，Dave陪外甥參加幼稚園的學校旅行，遇上美女教師Caroline，單身Dave立即出盡渾身解數冧女，誰知旅行搞手Teddy卻老是常出現做電燈膽。更令Dave始料不及的是附近一個軍事基地實驗失敗，殺出一班喪屍空群而出襲地球。Dave、Caroline和Teddy手無寸鐵，還要帶著一班幼稚園學生，他們必須合力抵擋喪屍，保護稚子，力求全身而退。
